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CAS No. : 434938-41-7

Biological Activity:K41498 is a potent and highly selective CRF2 receptor antagonist with Ki values of 0.66 nM, 0.62 nM and 425 nM for human CRF, CRF and CRF1 receptors respectively. K41498 is an analogues of antisauvagine-30 (aSvg-30), inhibits sauvagine-stimulated cAMP accumulation in hCRF– and hCRF-expressing cells. K41498 can be used for hypotension study.

Research Area:Cardiovascular Disease


Related Small Molecules:Stresscopin-related peptide (human);Sauvagine;CRF(6-33)(human) TFA;NBI-27914;Urocortin III, mouse;Emicerfont;R121919;CP 316311;Pexacerfont;Urotensin I TFA;Urocortin, rat TFA;Urocortin II, human TFA;α-Helical CRF(9-41);CP 376395;Urocortin, human;CRF, bovine TFA;Tildacerfont;Cortagine;Antisauvagine-30 TFA

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