Sunitinib-d10

For research use only. We do not sell to patients.

Sunitinib-d10

CAS No. : 1126721-82-1

Biological Activity:Sunitinib D10 (SU 11248 D10) is a deuterium labeled Sunitinib. Sunitinib is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively. Sunitinib, an ATP-competitive inhibitor, effectively inhibits autophosphorylation of Ire1α by inhibiting autophosphorylation and consequent RNase activation[2].

Research Area:Cancer

Targets:Autophagy|IRE1|VEGFR|Mitophagy|Apoptosis|PDGFR

Related Small Molecules:Physalin A;Bomedemstat ditosylate;(Z)-FeCP-oxindole;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;BJE6-106;Dinaciclib;VEGFR-2-IN-24;Ecteinascidin 770;MDM2-p53-IN-15;BMS-690514;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5

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