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Dapivirine
CAS No. : 244767-67-7
Biological Activity：Dapivirine (TMC120), the prototype of diarylpyrimidines (DAPY), is an orally active and nonnucleoside reverse transcriptase inhibitor (NRTI). Dapivirine (TMC120) binds directly to HIV-1 reverse transcriptase. Dapivirine (TMC120) regulates autophagy and induced Akt, Bad and SAPK/JNK activations[2].
Research Area：Infection
Targets：Autophagy|HIV|Apoptosis|Reverse Transcriptase
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Anti-Infection Compound Library;Apoptosis Compound Library;Clinical Compound Library;Antiviral Compound Library;Autophagy Compound Library;Drug Repurposing Compound Library;Orally Active Compound Library;Human Metabolite Library;
Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;BJE6-106;Dinaciclib;HIV-1 TAT (48-60);Ecteinascidin 770;MDM2-p53-IN-15;Seletracetam lithium;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;HIV-IN-2;Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5;Apoptosis inducer 9
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