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Vicriviroc maleate
CAS No. : 599179-03-0
Biological Activity：Vicriviroc maleate (SCH-417690 maleate; SCH-D maleate) is a potent, selective, oral bioavailable and CNS penetrated antagonist of CCR5, with a Ki of 2.5 nM, and also inhibits HIV-1 in PBMC cells, with IC90s of 3.3 nM (JrFL), 2.8 nM (ADA-M), 1.8 nM (301657), 4.9 nM (JV1083) and 10 nM (RU 570).
Research Area：Infection|Endocrinology
Targets：HIV|CCR
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Anti-Infection Compound Library;GPCR/G Protein Compound Library;Immunology/Inflammation Compound Library;Clinical Compound Library;Antiviral Compound Library;CNS-Penetrant Compound Library;Small Molecule Immuno-Oncology Compound Library;Drug Repurposing Compound Library;Endocrinology Compound Library;Orally Active Compound Library;Targeted Diversity Library;Anti-Pulmonary Fibrosis Compound Library;Chemokine Compound Library;
Related Small Molecules:HIV-1 TAT (48-60);Seletracetam lithium;HIV-IN-2;Triptonine B;LMD-009;FC131;Peritassine A;PF-04634817 succinate;Flavopiridol;TAT (48-57);FGI-106 tetrahydrochloride;(Z)-9-Propenyladenine;Apabetalone;Decanoyl-RVKR-CMK TFA;ONX-0914 TFA;Apelin-36(rat, mouse);Ulonivirine;Islatravir
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