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Olaparib
CAS No. : 763113-22-0
Biological Activity：Olaparib (AZD2281; KU0059436) is a potent and orally active PARP inhibitor with IC50s of 5 and 1 nM for PARP1 and PARP2, respectively. Olaparib is an autophagy and mitophagy activator[2][3][4].
Research Area：Cancer
Targets：PARP|Autophagy|Mitophagy
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Epigenetics Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;CNS-Penetrant Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Anti-COVID-19 Compound Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Anti-Breast Cancer Compound Library;Drug-Induced Liver Injury (DILI) Compound Library;Anti-Pancreatic Cancer Compound Library;Targeted Therapy Drug Library ;Mitochondria-Targeted Compound Library;Rare Diseases Drug Library;EMA-Approved Drug Library;FDA-Approved Anticancer Drug Library;Human Metabolite Library;Anti-Prostate Cancer Compound Library;Non-steroidal Anti-Inflammatory Compound Library;
Related Small Molecules:Curcumin;Rucaparib monocamsylate;AZD-2461;Senaparib;Dehydrocorydaline;Melatonin-d3;Rucaparib hydrochloride;Niraparib tosylate;G007-LK;PROTAC PARP1 degrader;UPF 1069;Resveratrol;Clioquinol;DP-C-4;Δ5-Avenasterol-d4;Betulinic acid;PARP14 inhibitor H10;Matrine;CEP-9722;Sulfosuccinimidyl oleate;Hemin;E7449;PARP1-IN-11;Polydatin
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