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CAS No. : 123663-49-0

Biological Activity:Iguratimod is an antirheumatic agent, acts as an inhibitor of COX-2, with an IC50 of 20 μM (7.7 μg/mL), but shows no effect on COX-1. Iguratimod also inhibits macrophage migration inhibitory factor (MIF) with an IC50 of 6.81 μM.

Research Area:Inflammation/Immunology

Targets:Macrophage migration inhibitory factor (MIF)|COX

Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;FDA-Approved Drug Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;NMPA-Approved Drug Library;Pyroptosis Compound Library;FDA Approved & Pharmacopeial Drug Library;Anti-Pancreatic Cancer Compound Library;Rare Diseases Drug Library;Anti-Colorectal Cancer Compound Library ;Antidepressant Compound Library;Human Metabolite Library;Anti-Prostate Cancer Compound Library;Non-steroidal Anti-Inflammatory Compound Library;

Related Small Molecules:Akt/NF-κB/JNK-IN-1;COX-2/5-LOX-IN-3;Ampyrone;COX-2-IN-24;Zaltoprofen-d7;α-Vitamin E-d6;1-Hydroxy-ibuprofen;MIF-IN-3;Asaraldehyde;(-)-Epicatechin;20(S)-Ginsenoside Rg3;Ginsenoside Rd;Nimesulide D5;COX-2/5-LOX-IN-1;S-(+)-Marmesin;Tazofelone;Catechin-13C3;MIF098;Diclofenac-d4;Proglumetacin;Ethoxycoronarin D;Phenidone;Fenbufen-d9;COX-2-IN-6;Anti-inflammatory agent 9

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