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Fenofibric acid

CAS No. : 42017-89-0

Biological Activity：Fenofibric acid, an active metabolite of fenofibrate, is a PPAR activitor, with EC₅₀s of 22.4 µM, 1.47 µM, and 1.06 µM for PPARα, PPARγ and PPARδ, respectively; Fenofibric acid also inhibits COX-2 enzyme activity, with an IC₅₀ of 48 nM.

Research Area：Metabolic Disease

Targets：PPAR|COX

Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Immunology/Inflammation Compound Library;FDA-Approved Drug Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Anti-COVID-19 Compound Library;Endoplasmic Reticulum Stress Compound Library;Pyroptosis Compound Library; Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Drug-Induced Liver Injury (DILI) Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Obesity Compound Library;Transcription Factor-Targeted Library;Lipid Metabolism Compound Library ;Anti-Colorectal Cancer Compound Library ;Antidepressant Compound Library;Human Metabolite Library;Anti-Prostate Cancer Compound Library;Nuclear Receptor Compound Library;Osteogenesis Compound Library;Cancer Stem Cells Compound Library;

Related Small Molecules:Akt/NF-κB/JNK-IN-1;COX-2/5-LOX-IN-3;Ampyrone;COX-2-IN-24;Falcarindiol;5-Aminosalicylic Acid-D3 hydrochloride;Retinoic acid;Zaltoprofen-d7;PPARγ agonist 7;α-Vitamin E-d6;1-Hydroxy-ibuprofen;Asaraldehyde;Licarin B;(-)-Epicatechin;Mifobate;20(S)-Ginsenoside Rg3;Ginsenoside Rd;Nimesulide D5;COX-2/5-LOX-IN-1;Daidzein-d4;S-(+)-Marmesin;Tazofelone;Ciglitazone;Catechin-13C3;MK-886;Diclofenac-d4

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