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B-Raf IN 8

CAS No. : 1215313-19-1

Biological Activity：B-Raf IN 8 (compound 7g) is a potent B-Raf inhibitor, with an IC₅₀ of 70.65 nM. B-Raf IN 8 exhibits antitumor activity against hepatocellular carcinoma (HEPG-2), colon carcinoma (HCT-116), mammary gland (MCF-7) and human prostate cancer (PC-3) cells, with IC₅₀ values of 9.78, 13.78, 18.52 and 29.85 µM.

Research Area：Cancer

Targets：Raf

Related Small Molecules:Avutometinib;AZ 628;Everafenib;L-779450;Raf inhibitor 1;PLX-4720;RRD-251;TAK-632;Encorafenib;RAF mutant-IN-1;AD80;CCT241161;PLX7904;RAF-IN-1;EGFR/BRAFV600E-IN-1;MCP110;GDC-0879;B-Raf IN 1;R18;Rineterkib

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