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8α,9α-Epoxycoleon-U-quinone
CAS No. : 93800-59-0
Biological Activity：8α,9α-Epoxycoleon-U-quinone (compound 3) is a p-glycoprotein (P-gp) regulator that is selective for cancer cells (SI=2.0). 8α,9α-Epoxycoleon-U-quinone effectively inhibits P-gp activity in NCI-H460/R cells. 8α,9α-Epoxycoleon-U-quinone also reverses the resistance of cancer cells to Doxorubicin (DOX) (HY-15142A) and enhances the anticancer effect of DOX.
Research Area：Cancer
Targets：P-glycoprotein
Related Small Molecules:Biricodar;P-gp inhibitor 4;Sinapine thiocyanate;Dofequidar fumarate;Elacridar;Coniferyl ferulate;Anticancer agent 50;Valspodar;P-gp inhibitor 1;Boeravinone B;Solamargine;Polyoxyethylene stearate;TTT-28;CP-100356 hydrochloride;Epoxylathyrol;Chrysosplenetin;Zamicastat;Tariquidar;P-gp modulator 3;Roemerine;Coleon-U-quinone;Zosuquidar trihydrochloride;Encequidar;P-gp modulator 1
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