Olanzapine

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Olanzapine

CAS No. : 132539-06-1

Biological Activity:Olanzapine (LY170053) is a selective, orally active monoaminergic antagonist with high affinity binding to serotonin H1, 5HT2A/2C, 5HT3, 5HT6 (Ki=7, 4, 11, 57, and 5 nM, respectively), dopamine D1-4 (Ki=11 to 31 nM), muscarinic M1-5 (Ki=1.9-25 nM), and adrenergic α1 receptor (Ki=19 nM). Olanzapine is an atypical antipsychotic[2].

Research Area:Neurological Disease|Cancer

Targets:Dopamine Receptor|Adrenergic Receptor|5-HT Receptor|Autophagy|mAChR|Mitophagy|Apoptosis

Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Apoptosis Compound Library;GPCR/G Protein Compound Library;Neuronal Signaling Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;CNS-Penetrant Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Anti-COVID-19 Compound Library;NMPA-Approved Drug Library;Orally Active Compound Library;Neurotransmitter Receptor Compound Library;FDA Approved & Pharmacopeial Drug Library;Anti-Alzheimer’s Disease Compound Library;Drug-Induced Liver Injury (DILI) Compound Library;Anti-Parkinson’s Disease Compound Library;Neurodegenerative Disease-related Compound Library;Mitochondria-Targeted Compound Library;Rare Diseases Drug Library;Antidepressant Compound Library;EMA-Approved Drug Library;5-HT Receptor Compound Library;FDA-Approved Anticancer Drug Library;Human Metabolite Library;Coagulation and Anti-coagulation Compound Library;

Related Small Molecules:VU0357017 hydrochloride;Physalin A;Bomedemstat ditosylate;F 13714;Enpp/Carbonic anhydrase-IN-1;Alizapride hydrochloride;GK563;Calpeptin;Thioproperazine;Lobetyolin;Mosapride-d5;Todralazine;BJE6-106;Bromopride-d3;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;TBPB

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