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Rineterkib hydrochloride
CAS No. : 1715025-34-5
Biological Activity：Rineterkib hydrochloride (compound B) is an orally available ERK1 and ERK2 inhibitor in the treatment of a proliferative disease characterized by activating mutations in the MAPK pathway. The activity is particularly related to the treatment of KRAS-mutant NSCLC, BRAF-mutant NSCLC, KRAS-mutant pancreatic cancer, KRAS-mutant colorectal cancer (CRC) and KRAS-mutant ovarian cancer. Rineterkib hydrochloride can also inhibit RAF[2].
Research Area：Cancer
Targets：Raf|ERK
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;
Related Small Molecules:Avutometinib;AZ 628;Corynoxeine;Temuterkib;Everafenib;CKLF1-C27;LM22B-10;L-779450;ERK5-IN-4;Pachymic acid;Raf inhibitor 1;MAP855;6-OAU;VX-11e;Pluripotin;2,5-Dihydroxyacetophenone;Astragaloside IV;PLX-4720;RRD-251;B-Raf IN 8;ERK1/2 inhibitor 1;TAK-632;Encorafenib;Longdaysin
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