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MK-5046
CAS No. : 1022152-70-0
Biological Activity：MK-5046 is a potent, selective and orally active Bombesin receptor subtype-3 (BRS-3) allosteric agonist with an IC50 and an EC50 value of 27 and 25 nM for hBRS-3, respectively. MK-5046 inhibits food intake and reduces body weight of diet-induced obese (DIO) mouse models. MK-5046 can be used for the research of obesity[2][3].
Research Area：Metabolic Disease
Targets：Bombesin Receptor
Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Targeted Diversity Library;
Related Small Molecules:PD176252;Bombesin;RC-3095;BA 1;BIM-26226;ML-18;Kuwanon H;Litorin;Ranatensin;Kuwanon G;PD 168368
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