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Lacidipine

CAS No. : 103890-78-4

Biological Activity：Lacidipine is an orally active and highly selective L-type calcium channel blocker that acts on smooth muscle calcium channels, primarily dilates peripheral arteries, reduces peripheral resistance, and has long-lasting anti-hypertensive activity. Lacidipine protects HKCs from apoptosis induced by ATP depletion and recovery by modulating the caspase-3 pathway. Lacidipine can be used in studies of hypertension, atherosclerosis and acute kidney injury (AKI)^[2].

Research Area：Cardiovascular Disease

Targets：Calcium Channel|Reactive Oxygen Species|Caspase|Apoptosis

Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Apoptosis Compound Library;Immunology/Inflammation Compound Library;Membrane Transporter/Ion Channel Compound Library;Metabolism/Protease Compound Library;Neuronal Signaling Compound Library;NF-κB Signaling Compound Library;Stem Cell Signaling Compound Library;FDA-Approved Drug Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Antioxidant Compound Library;Reprogramming Compound Library;Oxygen Sensing Compound Library;Anti-Cardiovascular Disease Compound Library;Ferroptosis Compound Library;NMPA-Approved Drug Library;Pyroptosis Compound Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Neuroprotective Compound Library;Anti-Parkinson’s Disease Compound Library;Neurodegenerative Disease-related Compound Library;Mitochondria-Targeted Compound Library;Calcium Channel Blocker Library;

Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Physalin A;Bomedemstat ditosylate;Chitoheptaose heptahydrochloride;Enpp/Carbonic anhydrase-IN-1;GK563;Benidipine hydrochloride;Calpeptin;Lobetyolin;CaV1.3 antagonist-1;14-Deoxyandrographolide;N-Acetyl-D-cysteine;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;CYPMPO;Xevinapant;Mangiferin

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