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RPR121056
CAS No. : 181467-56-1
Biological Activity:RPR121056 (APC) is a metabolite of Irinotecan (CPT-11), which is generated by CYP3A4. Irinotecan (CPT-11) is an antineoplastic agent that inhibits topoisomerase type I, causing cell death, and is widely used in the treatment of colorectal cancer. Irinotecan also directly inhibits AChE.
Research Area:Cancer
Targets:Topoisomerase|Cholinesterase (ChE)
Related Screening Libraries:Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Neuronal Signaling Compound Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Anti-Lung Cancer Compound Library;Anti-Colorectal Cancer Compound Library ;Human Metabolite Library;
Related Small Molecules:Gepotidacin;Topoisomerase I/II inhibitor 3;Piperilate;(R)-Camptothecin-d5;BuChE-IN-5;AChE/BChE-IN-10;Topoisomerase II inhibitor 8;FLT3-IN-13;Timosaponin AIII;TP3011;Trimyristin;AChE-IN-10;TAS-103 dihydrochloride;Isoimperatorin;Pseudocoptisine chloride;Itopride-d6 hydrochloride;Sinapine thiocyanate;sEH/AChE-IN-1;Rebeccamycin;AChE-IN-11;Heliosupine;(-)-Cyclopenin
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