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Mpro inhibitor N3 hemihydrate

Biological Activity：Mpro inhibitor N3 hemihydrate is a potent inhibitor of SARS-CoV-2 Mpro with an EC₅₀ of 16.77 μM for SARS-CoV-2. Mpro inhibitor N3 hemihydrate specifically inhibits Mpro from multiple coronaviruses, including SARS-CoV and MERS-CoV. Mpro inhibitor N3 hemihydrate displays inhibition against HCoV-229E, FIPV, and MHV-A59 with individual IC₅₀ of 4.0 μM, 8.8 μM, and 2.7 μM, respectively^[2].

Research Area：Infection

Targets：Virus Protease|SARS-CoV

Related Screening Libraries:Bioactive Compound Library Plus;Anti-Infection Compound Library;Antiviral Compound Library;

Related Small Molecules:SRPIN340;ZIKV-IN-4;Aminothiazole;CYP2C9/CYP2C19-IN-1;SARS-CoV-2-IN-33;GRL-0496;Grazoprevir potassium salt;SARS-CoV-2-IN-19;Molnupiravir;SARS-CoV-2 Mpro-IN-3;L-Lysine;MM3122;Ketotifen fumarate;SARS-CoV-2-IN-16;Thapsigargin;L-Lysine-13C6,15N2,d9 dihydrochloride;INSCoV-614(1B);4E2RCat;Anti-SARS-CoV-2 Spike mAb (CR3022);GNF-2;Bemnifosbuvir hemisulfate;Kansuinine B

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