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Casopitant mesylate
CAS No. : 414910-30-8
Biological Activity：Casopitant mesylate (GW679769B) is a potent, selective, brain permeable and orally active neurokinin 1 (NK1) receptor antagonist. Casopitant mesylate is a second in the class of antiemetics that acts to antagonise the emetogenic effect of substance P. Casopitant mesylate is also a substrate and a weak-to-moderate inhibitor of CYP3A4. Casopitant mesylate can be used for chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea and vomiting (PONV)[2].
Research Area：Neurological Disease
Targets：Neurokinin Receptor|Cytochrome P450
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Related Small Molecules:(β-Ala8)-Neurokinin A (4-10);SR9186;AMG-208;Talnetant hydrochloride;CYP1B1-IN-1;CYP2C9/CYP2C19-IN-1;Pavinetant;Hypericin;MEN11467;Galeterone;Ranitidine;Bergapten;Ginsenoside Rd;AS1810722;Isoglycycoumarin;Polygalaxanthone III;Phenyltoloxamine;(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P;Ezutromid;Seviteronel;β-Apo-8′-carotenal;Diosmetin-d3;EDP-305;Fipronil;Vapreotide acetate
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