Tag: Inhibitor|Inducer

For research use only. We do not sell to patients. Imipramine-d3 hydrochloride CAS No. : 112898-42-7 Biological Activity：Imipramine-d3 (hydrochloride) is deuterium labeled Imipramine (hydrochloride). Imipramine is an orally active tertiary amine tricyclic antidepressant. Imipramine is a Fascin1 inhibitor with antitumor activities. Imipramine also inhibits serotonin transporter with an IC50 value of 32 nM. Imipramine stimulates […]

For research use only. We do not sell to patients. 3-Dehydrotrametenolic acid CAS No. : 29220-16-4 Biological Activity：3-​Dehydrotrametenolic acid, isolated from the sclerotium of Poria cocos, is a lactate dehydrogenase (LDH) inhibitor. 3-​Dehydrotrametenolic acid promotes adipocyte differentiation in vitro and acts as an insulin sensitizer in vivo. 3-​Dehydrotrametenolic acid induces apoptosis and has anticancer activity[2]. […]

For research use only. We do not sell to patients. PFI-90 CAS No. : 53995-62-3 Biological Activity：PFI-90 is a selective inhibitor of histone demethylase (KDM3B) that inhibits PAX3-FOXO1 action. PFI-90 induces apoptosis and myogenic differentiation, resulting in the cell death increased. PFI-90 has the potential for the antitumor activity. (patent WO2021101929A1). Research Area：Cancer Targets：Apoptosis|Histone Demethylase […]

For research use only. We do not sell to patients. Topotecan hydrochloride hydrate CAS No. : 1044663-62-8 Biological Activity：Topotecan hydrochloride hydrate is an orally active and potent Topoisomerase I inhibitor. Topotecan hydrochloride hydrate induces cell cycle arrest in G0/G1 and S phases and promotes apoptosis. Topotecan hydrochloride hydrate shows anticancer activity. Research Area：Cancer Targets：Topoisomerase|Autophagy|Apoptosis Related […]

For research use only. We do not sell to patients. Cediranib maleate CAS No. : 857036-77-2 Biological Activity：Cediranib maleate (AZD-2171 maleate) is a highly potent, orally available VEGFR inhibitor with IC50s of

For research use only. We do not sell to patients. Sildenafil-d8 CAS No. : 951385-68-5 Biological Activity：Sildenafil-d8 (UK-92480-d8) is the deuterium labeled Sildenafil. Sildenafil (UK-92480) is a potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM[2]. Research Area：Cardiovascular Disease|Cancer Targets：Phosphodiesterase (PDE)|Autophagy|Apoptosis Related Small Molecules:Physalin A;Bomedemstat ditosylate;Senazodan hydrochloride;(E/Z)-HA155;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;ATX inhibitor 22;Carbazeran citrate;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase […]

For research use only. We do not sell to patients. Aliskiren-d6 hemifumarate Biological Activity：Aliskiren D6 hemifumarate (CGP 60536 D6 hemifumarate) is a deuterium labeled Aliskiren hemifumarate. Aliskiren hemifumarate is a direct and orally active renin inhibitor with an IC50 of 1.5 nM[2]. Research Area：Cancer|Cardiovascular Disease Targets：Autophagy|Renin Related Small Molecules:Remikiren;Handle region peptide, rat;Renin inhibitor-1;SPH3127;Araloside A;Enalkiren;VTP-27999 TFA;Lyciumin […]

For research use only. We do not sell to patients. LDCA CAS No. : 349106-80-5 Biological Activity：LDCA is a dual-hit metabolic modulator and inhibits LDH-A enzyme activity to stimulate apoptosis in the malignant population. LDCA can be used for the research of oncogenic progression. Research Area：Cancer Targets：Lactate Dehydrogenase|Apoptosis Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase […]

For research use only. We do not sell to patients. CT1-3 CAS No. : 2460738-32-1 Biological Activity：CT1-3 is a potent anticancer agent. CT1-3 induces mitochondria-mediated apoptosis by regulating JNK/Bcl-2/Bax/XIAP pathway. CT1-3 suppresses the epithelial mesenchymal transition (EMT) potential of human cancer cells (HCCs) via regulating the E-cadherin/Snail axis, thus inhibits tumorigenesis. CT1-3 has a strong […]

For research use only. We do not sell to patients. Efavirenz CAS No. : 154598-52-4 Biological Activity：Efavirenz (DMP 266) is a potent inhibitor of the wild-type HIV-1 reverse transcriptase with a Ki of 2.93 nM and exhibits an IC95 of 1.5 nM for the inhibition of HIV-1 replicative spread in cell culture. Research Area：Infection|Cancer Targets：Parasite|Autophagy|HIV|Endogenous […]