Tag: Inhibitor|Antagonist

For research use only. We do not sell to patients. Fluphenazine-d8 CAS No. : 1323633-98-2 Biological Activity：Fluphenazine-d8 is the deuterium labeled Fluphenazine. Fluphenazine is a potent, orally active phenothiazine-based dopamine receptor antagonist. Fluphenazine blocks neuronal voltage-gated sodium channels. Fluphenazine acts primarily through antagonism of postsynaptic dopamine-2 receptors in mesolimbic, nigrostriatal, and tuberoinfundibular neural pathways. Fluphenazine […]

For research use only. We do not sell to patients. Fluphenazine dimaleate CAS No. : 3093-66-1 Biological Activity：Fluphenazine dimaleate is a potent, orally active phenothiazine-based dopamine receptor antagonist. Fluphenazine dimaleate blocks neuronal voltage-gated sodium channels. Fluphenazine dimaleate acts primarily through antagonism of postsynaptic dopamine-2 receptors in mesolimbic, nigrostriatal, and tuberoinfundibular neural pathways. Fluphenazine dimaleate can […]

For research use only. We do not sell to patients. Maraviroc-d6 CAS No. : 1033699-22-7 Biological Activity：Maraviroc-d6 (UK-427857-d6) is the deuterium labeled Maraviroc. Maraviroc (UK-427857) is a selective CCR5 antagonist with activity against human HIV[2]. Research Area：Inflammation/Immunology|Cancer|Endocrinology Targets：HIV|CCR Related Small Molecules:HIV-1 TAT (48-60);Seletracetam lithium;HIV-IN-2;Triptonine B;LMD-009;FC131;Peritassine A;PF-04634817 succinate;Flavopiridol;TAT (48-57);FGI-106 tetrahydrochloride;(Z)-9-Propenyladenine;Apabetalone;Decanoyl-RVKR-CMK TFA;ONX-0914 TFA;Apelin-36(rat, mouse);Ulonivirine;Islatravir Trending products：Recombinant Proteins  […]

For research use only. We do not sell to patients. Maraviroc CAS No. : 376348-65-1 Biological Activity：Maraviroc (UK-427857) is a selective CCR5 antagonist with activity against human HIV. Research Area：Inflammation/Immunology|Cancer|Endocrinology Targets：HIV|CCR Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Anti-Infection Compound Library;GPCR/G Protein Compound Library;Immunology/Inflammation Compound Library;FDA-Approved Drug […]

For research use only. We do not sell to patients. Loxapine succinate CAS No. : 27833-64-3 Biological Activity：Loxapine succinate is an orally active dopamine inhibitor, 5-HT receptor antagonist and also a dibenzoxazepine anti-psychotic agent. Loxapine can also suppresses bacterial efflux pump activity and inhibit intracellular multiple-antibiotic-resistant Salmonella enterica serovar Typhimurium in macrophages[4][6]. Research Area：Infection|Neurological Disease […]

For research use only. We do not sell to patients. Azelastine-13C,d3 hydrochloride Biological Activity：Azelastine-13C,d3 hydrochloride is the 13C- and deuterium labeled Azelastine hydrochloride. Azelastine-13C,d3 hydrochloride, an antihistamine, is a potent and selective histamine 1 (H1) antagonist. Azelastine-13C,d3 hydrochloride can be used for the research of allergic rhinitis, asthma, diabetic hyperlipidemic and SARS-CoV-2[2][3][4]. Research Area：Infection|Endocrinology|Metabolic Disease|Inflammation/Immunology […]

For research use only. We do not sell to patients. β-Spaglumic acid CAS No. : 4910-46-7 Biological Activity：β-Spaglumic acid (β-NAAG) is a competitive NAAG peptidase inhibitor (Ki=1 µM) that protects spinal cord neurons from excitotoxicity and hypoxic damage. β-Spaglumic acid is also a selective mGluR3 antagonist (mGluR3 receptor functions to regulate activity-dependent synaptic potentiation in […]

For research use only. We do not sell to patients. Oxatomide CAS No. : 60607-34-3 Biological Activity：Oxatomide is a potent and orally active dual H1-histamine receptor and P2X7 receptor antagonist with antihistamine and anti-allergic activity. Oxatomide almost completely blocks the ATP-induced current in human P2X7 receptors (IC50 of 0.95 μM). Oxatomide inhibits ATP-induced Ca2+ influx […]

For research use only. We do not sell to patients. Mavorixafor CAS No. : 558447-26-0 Biological Activity：Mavorixafor (AMD-070) is a potent, selective and orally available CXCR4 antagonist, with an IC50 value of 13 nM against CXCR4 125I-SDF binding, and also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs with an […]

For research use only. We do not sell to patients. FC131 TFA Biological Activity：FC131 TFA is a CXCR4 antagonist, inhibits [125I]-SDF-1 binding to CXCR4, with an IC50 of 4.5 nM. Anti-HIV activity. Research Area：Infection Targets：CXCR|HIV Related Screening Libraries:Bioactive Compound Library Plus;Peptide Library; Related Small Molecules:Nicotinamide N-oxide;HIV-1 TAT (48-60);Seletracetam lithium;HIV-IN-2;Triptonine B;FC131;Peritassine A;CXCR4 antagonist 2;Flavopiridol;AMG 487 (S-enantiomer);TAT […]