Tag: Inducer|Antagonist|Inhibitor

For research use only. We do not sell to patients. Flupentixol dihydrochloride CAS No. : 2413-38-9 Biological Activity：Flupentixol is an orally active D1/D2 dopamine receptor antagonist and new PI3K inhibitor (PI3Kα IC50=127 nM). Flupentixol shows anti-proliferative activity to cancer cells and induces apoptosis. Flupentixol can also be used in schizophrenia, anxiolytic and depressive research[2][3]. Research […]

For research use only. We do not sell to patients. Peimisine hydrochloride CAS No. : 900498-44-4 Biological Activity：Peimisine (Ebeiensine) hydrochloride is a muscarinic M receptor antagonist and angiotensin converting enzyme (ACE) inhibitor. Peimisine hydrochloride shows anti-tumor, anti-inflammatory, antihypertensive activities. Peimisine can induce apoptosis and be used in cough and asthma research[2][3]. Research Area：Cancer|Inflammation/Immunology|Cardiovascular Disease Targets：Angiotensin-converting […]

For research use only. We do not sell to patients. Novobiocin sodium CAS No. : 1476-53-5 Biological Activity：Novobiocin (Albamycin) sodium is a potent and orally active antibiotic. Novobiocin sodium also is a DNA gyrase inhibitor and a heat shock protein 90 (Hsp90) antagonist. Novobiocin sodium has the potential for the research of highly beta-lactam-resistant pneumococcal […]

For research use only. We do not sell to patients. Fasudil dihydrochloride CAS No. : 203911-27-7 Biological Activity：Fasudil (HA-1077; AT877) dihydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 μM for ROCK1, IC50s of 0.158 μM and 4.58 μM, 12.30 μM, 1.650 μM for ROCK2 […]

For research use only. We do not sell to patients. Mefloquine CAS No. : 53230-10-7 Biological Activity：Mefloquine (Mefloquin), an orally active and potent quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor. Mefloquine is also a K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM. Mefloquine can be used for malaria, systemic lupus erythematosus and […]

For research use only. We do not sell to patients. Thioridazine hydrochloride CAS No. : 130-61-0 Biological Activity：Thioridazine hydrochloride, an orally active antagonist of the dopamine receptor D2 family proteins, exhibits potent anti-psychotic and anti-anxiety activities. Thioridazine hydrochloride is also a potent inhibitor of PI3K-Akt-mTOR signaling pathways with anti-angiogenic effect. Thioridazine hydrochloride shows antiproliferative and […]

For research use only. We do not sell to patients. Perphenazine CAS No. : 58-39-9 Biological Activity：Perphenazine is an orally active dopamine receptor and histamine-1 receptor antagonist, with Ki values of 0.56 nM (D2), 0.43 nM (D3), 6 nM (5-HT2A), respectively. Perphenazine also binds to Alpha-1A adrenergic receptor. Perphenazine inhibits cancer cell proliferation, and induces […]

For research use only. We do not sell to patients. Mifepristone-d3 CAS No. : 1228097-18-4 Biological Activity：Mifepristone-d3 (RU486-d3) is the deuterium labeled Mifepristone. Mifepristone (RU486) is a progesterone receptor (PR) and glucocorticoid receptor (GR) antagonist with IC50s of 0.2 nM and 2.6 nM in in vitro assay. Research Area：Endocrinology|Cancer Targets：Autophagy|Glucocorticoid Receptor|Progesterone Receptor|NO Synthase Related Small […]

For research use only. We do not sell to patients. Chelerythrine CAS No. : 34316-15-9 Biological Activity：Chelerythrine is a natural alkaloid, acts as a potent and selective Ca2+/phospholopid-dependent PKC antagonist, with an IC50 of 0.7 μM. Chelerythrine has antitumor, antidiabetic and anti-inflammatory activity[2]. Chelerythrine inhibits the BclXL-Bak BH3 peptide binding with IC50 of 1.5 μM […]

For research use only. We do not sell to patients. Thioridazine-d3 2-Sulfone CAS No. : 1329652-09-6 Biological Activity：Thioridazine-d3 2-Sulfone is the deuterium labeled Thioridazine hydrochloride. Thioridazine hydrochloride, an orally active antagonist of the dopamine receptor D2 family proteins, exhibits potent anti-psychotic and anti-anxiety activities. Thioridazine hydrochloride is also a potent inhibitor of PI3K-Akt-mTOR signaling pathways […]