Tag: Antagonist

For research use only. We do not sell to patients. WIN 64338 hydrochloride CAS No. : 163727-74-0 Biological Activity：WIN 64338 hydrochloride is a potent, selective, nonpeptide competitive antagonist of bradykinin B2 receptor. WIN 64338 hydrochloride inhibits [3H]-Bradykinin binding to the bradykinin B2 receptor on human IMR-90 cells with a Ki of 64 nM. WIN 64338 […]

For research use only. We do not sell to patients. K-(D-1-Nal)-FwLL-NH2 CAS No. : 1394288-22-2 Biological Activity：K-(D-1-Nal)-FwLL-NH2 is a high affinity, potent and inverse ghrelin receptor agonist (EC50=3.4 nM, Ki=4.9 nM). K-(D-1-Nal)-FwLL-NH2 can be used for the research of obesity. Research Area：Metabolic Disease Targets：GHSR Related Small Molecules:Relamorelin acetate;(αR,8aS)-GSK1614343;Capromorelin Tartrate;BMS-604992 dihydrochloride;Macimorelin;TM-N1324;L-692585;Anamorelin hydrochloride;Obestatin(rat) TFA;GHRF, bovine;des-​Gln14-​Ghrelin TFA;des-​Gln14-​Ghrelin;Ibutamoren Mesylate;GHRF, […]

For research use only. We do not sell to patients. Raclopride-d5 hydrochloride CAS No. : 1217623-85-2 Biological Activity：Raclopride-d5 (hydrochloride) is the deuterium labeled Raclopride. Raclopride is a dopamine D2/D3 receptor antagonist, which binds to D2 and D3 receptors with dissociation constants (Kis) of 1.8 nM and 3.5 nM, respectively, but has a very low affinity […]

For research use only. We do not sell to patients. Ziconotide acetate CAS No. : 914454-03-8 Biological Activity：Ziconotide acetate (SNX-111 acetate), a peptide, is a potent and selective block of N-type calcium channels antagonist. Ziconotide acetate reduces synaptic transmission, and can be used for chronic pain research. Research Area：Inflammation/Immunology|Cardiovascular Disease|Cancer Targets：Calcium Channel Related Screening Libraries:Drug […]

For research use only. We do not sell to patients. DIPPA hydrochloride CAS No. : 155512-52-0 Biological Activity：DIPPA (hydrochloride) is an irreversible, long-lasting, selective and high affinity κ-opioid receptor antagonist. DIPPA (hydrochloride) can be used for the research of anxiety and antidepressant[2][3][4]. Research Area：Neurological Disease Targets：Opioid Receptor Related Small Molecules:ORL1 antagonist 1;Loperamide-d6 N-Oxide;Deltorphin 2 TFA;Nalfurafine;β-Lipotropin […]

For research use only. We do not sell to patients. Protease-Activated Receptor-1 antagonist 2 CAS No. : 1454588-34-1 Biological Activity：Protease-Activated Receptor-1 antagonist 2 is an orally active protease-activated receptor-1 (PAR-1) antagonist, with an IC50 value of 7 nM. Protease-Activated Receptor-1 antagonist 2 has favorable pharmacokinetic properties which is useful in the research of cardiovascular disease (CVD), […]

For research use only. We do not sell to patients. A-1165442 CAS No. : 1221443-94-2 Biological Activity：A-1165442 is a potent, competitive and orally available TRPV1 antagonist with an IC50 of 9 nM for human TRPV1. Research Area：Neurological Disease Targets：TRP Channel Related Screening Libraries:Bioactive Compound Library Plus; Related Small Molecules:V116517;GSK2332255B;Pregnenolone monosulfate sodium;TRPC5-IN-4;OptoBI-1;SB-705498;TRPC3/6-IN-1;ABT-239;Pyr3;Asivatrep;Ononetin;TRPM8 antagonist 3;FEMA 4809;Hydroxy-α-sanshool;GsMTx4 TFA;TRPM4-IN-1;Palvanil;Pregnenolone […]

For research use only. We do not sell to patients. 4-(tert-Butyl)-benzhydroxamic Acid CAS No. : 62034-73-5 Biological Activity：4-(tert-Butyl)-benzhydroxamic Acid is a PqsR antagonist with IC50s of 12.5 μM and 23.6 μM for E. coli and P. aeruginosa, respectively. 4-(tert-Butyl)-benzhydroxamic Acid reduces the production of the virulence factor pyocyanin in P. aeruginosa with an IC50 of […]

For research use only. We do not sell to patients. BGC20-761 CAS No. : 17375-63-2 Biological Activity：BGC20-761 is a selecvtive 5-HT6 and dopamine receptor antagonist (human receptor Ki values: 5-HT6 (20 nM), 5-HT2A (69 nM), D2 (140 nM). BGC20-761, can enhance long-term memory. BGC20-761 has potential utility as an antipsychotic agent. Research Area：Neurological Disease Targets：Dopamine […]

For research use only. We do not sell to patients. Dopropidil CAS No. : 79700-61-1 Biological Activity：Dopropidil is a novel anti-anginal calcium ion modulating agent, possessing intracellular calcium antagonist activity and anti-ischemic effects in several predictive animal models. Research Area：Cardiovascular Disease Targets：Calcium Channel Related Small Molecules:Benidipine hydrochloride;CaV1.3 antagonist-1;14-Deoxyandrographolide;(Rac)-MEM 1003;Glaucine;Efonidipine hydrochloride monoethanolate;L-Ascorbic acid sodium salt;Brompheniramine-d6 maleate;MRS […]