Tag: Agonist

For research use only. We do not sell to patients. trans-Cevimeline hydrochloride CAS No. : 107220-29-1 Biological Activity：Trans-Cevimeline (AF102A) (hydrochloride), as a trans-isomer of AF102B, is a M1 selective cholinergic agonist. Trans-Cevimeline (AF102A) (hydrochloride) can be used for the research of Alzheimer’s disease. Research Area：Neurological Disease Targets：mAChR Related Small Molecules:VU0357017 hydrochloride;TBPB;Imidafenacin;Sabcomeline;MK-6884;Brompheniramine-d6 maleate;Navafenterol saccharinate;DREADD agonist 21;Cyclobuxine […]

For research use only. We do not sell to patients. Prednisolone acetate CAS No. : 52-21-1 Biological Activity：Prednisolone acetate (Prednisolone 21-acetate) is an adrenal cortico hormones, with anti-inflammatory, anti-allergic and immune suppressive effects. Research Area：Inflammation/Immunology Targets：Glucocorticoid Receptor Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;FDA-Approved […]

For research use only. We do not sell to patients. Dobutamine tartrate CAS No. : 101626-66-8 Biological Activity：Dobutamine tartrate is a synthetic catecholamine that acts on α1-AR, β1-AR, β2-AR (α-1, β-1 andβ-2 adrenoceptors). Dobutamine tartrate is a selective β1-AR agonist, relatively weak activity at α1-AR and β2-AR. Dobutamine tartrate can increase cardiac output and correct […]

For research use only. We do not sell to patients. [D-Trp34]-Neuropeptide Y TFA Biological Activity：[D-Trp34]-Neuropeptide Y TFA is a potent and selective neuropeptide Y (NPY) Y5 receptor agonist. [D-Trp34]-Neuropeptide Y TFA is a significantly less potent agonist at the NPY Y1, Y2, Y4, and y6 receptors. [D-Trp34]-Neuropeptide Y TFA markedly increases food intake in rats[2]. […]

For research use only. We do not sell to patients. GW842166X CAS No. : 666260-75-9 Biological Activity：GW842166X is a potent and selective cannabinoid receptor 2 (CB2) agonist with IC50 values of 63 and 91 nM for human and rat CB2, respectively. Research Area：Inflammation/Immunology|Neurological Disease Targets：Cannabinoid Receptor Related Screening Libraries:Covalent Screening Library Plus;Clinical Compound Library Plus;Bioactive […]

For research use only. We do not sell to patients. TBPB CAS No. : 634616-95-8 Biological Activity：TBPB is an allosteric M1 mAChR agonist(EC50=289 nM) that regulates amyloid processing and produces antipsychotic-like activity in rats. Research Area：Neurological Disease Targets：mAChR Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Neuronal Signaling Compound Library;Neurotransmitter Receptor Compound Library; Related Small […]

For research use only. We do not sell to patients. BETP CAS No. : 1371569-69-5 Biological Activity：BETP is an agonist of glucagon-like peptide-1 (GLP-1) receptor, with EC50s of 0.66 and 0.755 μM for human and rat GLP-1 receptor, respectively. Research Area：Metabolic Disease Targets：GCGR Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library; Anti-diabetic Compound Library; […]

For research use only. We do not sell to patients. GSK2018682 CAS No. : 1034688-30-6 Biological Activity：GSK2018682 is an agonist for S1P1 and S1P5 receptor with pEC50s of 7.7 and 7.2, respectively, and has no agonist activity towards human S1P2, S1P3, or S1P4. GSK2018682 is used in the research of multiple sclerosis. Research Area：Inflammation/Immunology Targets：LPL […]

For research use only. We do not sell to patients. Sabcomeline CAS No. : 159912-53-5 Biological Activity：Sabcomeline (SB-202026) is a potent and functionally selective muscarinic M1 receptor partial agonist that improve cognition. Sabcomeline can be used for Alzheimer’s disease research[2]. Research Area：Neurological Disease Targets：mAChR Related Small Molecules:VU0357017 hydrochloride;TBPB;Imidafenacin;MK-6884;Brompheniramine-d6 maleate;Navafenterol saccharinate;DREADD agonist 21;Cyclobuxine D;Brompheniramine maleate;Dexetimide;Anisodamine hydrobromide;Anisotropine […]

For research use only. We do not sell to patients. Deflazacort-D5 Biological Activity：Deflazacort-D5 is the deuterium labeled Deflazacort. Deflazacort, a glucocorticoid, is an inactive prodrug and is converted rapidly to the active metabolite 21-desacetyldeflazacort. Deflazacort is used as an anti-inflammatory and immunosuppressant. Research Area：Inflammation/Immunology|Endocrinology Targets：Glucocorticoid Receptor Related Small Molecules:Glucocorticoid receptor agonist-2;AZD2906;Beclometasone dipropionate;ORIC-101;Clobetasone butyrate;Cortisone-d2;Clobetasone butyrate-d7;Cortisone-13C3;Glucocorticoid receptor […]