Tag: Activator

For research use only. We do not sell to patients. Salvianolic acid B CAS No. : 121521-90-2 Biological Activity：Salvianolic acid B is an active ingredient of Salvia miltiorrhiza, which has been widely applied in China for the management of various microcirculation-related disorders, such as cardiovascular disease, cerebrovascular disease, and diabetic vascular complication. Research Area：Cardiovascular Disease […]

For research use only. We do not sell to patients. PUMA BH3 TFA Biological Activity：PUMA BH3 (TFA) is a p53 upregulated modulator of apoptosis (PUMA) BH3 domain peptide, acts as a direct activator of Bak, with a Kd of 26 nM. Research Area：Cancer Targets：Bcl-2 Family Related Small Molecules:BI-3812;Pyridoclax;Dehydrocorydaline;Bufarenogin;Murizatoclax;Obatoclax;CYD-2-11;BM 957;(S)-Gossypol (acetic acid);A-385358;Mcl-1 inhibitor 6;S55746;Anticancer agent 63;MCL-1/BCL-2-IN-2;Anticancer […]

For research use only. We do not sell to patients. Mas7 CAS No. : 145854-59-7 Biological Activity：Mas7 (Mastoparan 7), a structural analogue of mastoparan, is an activator of heterotrimeric Gi proteins and its downstream effectors. Research Area：Neurological Disease|Cardiovascular Disease Targets：Others Related Screening Libraries:Bioactive Compound Library Plus;Peptide Library; Related Small Molecules:Immune initiator-1;Obiltoxaximab;DIBAC-GGFG-NH2CH2-Dxd;Cyanine5.5 maleimide chloride;Cymarin;Z-Glycine;2-Deoxy-2-fluoro-D-glucose-13C,d7;Water-18O;Fmoc-N-Me-D-Ala-OH;3,5-Diiodo-L-tyrosine;N3-Pen-Dde;Zimeldine-d6;Ornidazole diol;Nylidrin hydrochloride;PFI-653;N-Arachidonoyl […]

For research use only. We do not sell to patients. Pyributicarb CAS No. : 88678-67-5 Biological Activity：Pyributicarb, a carbamate-type herbicide, is a potent activator of both CYP3A4 gene and human pregnane X receptor (hPXR). Research Area：Inflammation/Immunology Targets：Cytochrome P450 Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Metabolism/Protease Compound Library;Anti-Aging Compound Library;Antioxidant Compound Library;Oxygen Sensing Compound Library;Nuclear […]

For research use only. We do not sell to patients. Hellebrigenin CAS No. : 465-90-7 Biological Activity：Hellebrigenin, one of bufadienolides belonging to cardioactive steroids, is isolated from traditional Chinese medicine Venenum Bufonis. Hellebrigenin induces DNA damage and cell cycle G2/M arrest. Hellebrigenin triggers mitochondria-mediated apoptosis. Research Area：Cancer Targets：Apoptosis Related Screening Libraries:Natural Product Library Plus;Bioactive Compound […]

For research use only. We do not sell to patients. Dehydroleucodine CAS No. : 36150-07-9 Biological Activity：Dehydroleucodine is a sesquiterpene lactone isolated from Gynoxys verrucosa. Dehydroleucodine is a mast cell stabilizer that inhibits tmast cell degranulation induced by compound 48/80. Dehydroleucodine inudces cells apoptosis, and has gastric ulcer inhibition and antileukemic effects[2][3]. Research Area：Cancer|Inflammation/Immunology Targets：Apoptosis […]

For research use only. We do not sell to patients. Pinacidil CAS No. : 60560-33-0 Biological Activity：Pinacidil is a potent activator of potassium channel. Pinacidil is an antihypertensive agent which hyperpolarises vascular smooth muscle by opening K+-channels. Pinacidil significantly improves the reperfusion function and cardiac compliance. Pinacidil has direct cardioprotective efficacy. Research Area：Cardiovascular Disease Targets：Potassium […]

For research use only. We do not sell to patients. Oct3/4-inducer-1 CAS No. : 1016535-83-3 Biological Activity：Oct3/4-inducer-1 (compound 2) is a potent Oct3/4 inducer. Oct3/4-inducer-1 promotes expression and stabilization of Oct3/4, and enhances its transcriptional activity in diverse human somatic cells. Research Area：Inflammation/Immunology Targets：Oct3/4 Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Stem Cell Signaling Compound […]

For research use only. We do not sell to patients. CP-628006 CAS No. : 305822-08-6 Biological Activity：CP-628006, a small molecule CFTR potentiator, restores ATP-dependent channel gating to the cystic fibrosis mutant G551D-CFTR. Research Area：Others Targets：CFTR Related Small Molecules:PG01;CFTR corrector 8;SRI-37240;Urocortin III (mouse) (free acid);NJH-2-056;Elexacaftor;GlyH-101;Cavosonstat;Kobusin;GLPG1837;(R)-Posenacaftor sodium;GLPG2451;CFTR corrector 9;CFTR corrector 2;Vanzacaftor;CFTR corrector 4;Posenacaftor sodium;NJH-2-057;KM11060;Nesolicaftor;Galicaftor;Tezacaftor;PPQ-102;SRI-41315;CFTR corrector 6 Trending […]

For research use only. We do not sell to patients. Lucidenic acid B CAS No. : 95311-95-8 Biological Activity：Lucidenic acid B is a natural compound isolated from Ganoderma lucidum, induces apoptosis of cancer cells, and causes the activation of caspase-9 and caspase-3, and cleavage of PARP. Lucidenic acid B does not affect the cell cycle […]