epigenetics modulation frontier
Master of Bioactive Molecules | Inhibitors, Screening Libraries & Proteins
Multiple Myeloma (MM) is linked to the JAK1 and JAK2 genes in its development, similar to myelofibrosis. Myelofibrosis is a clonal disorder that starts at the hematopoietic stem cell level.…
A new fluorescent suitane was engineered by integrating a T-shaped triphenylbenzimidazole axle with a dibenzocrown-8 ether-derived macrocycle through a template-directed supramolecular synthesis. The process began with the formation of a…
The successful application of hydrazone-based 2D-COF-1 in visible-light-driven aerobic oxidation underscores key design principles that are essential for developing high-performance covalent organic framework (COF)-based photocatalysts. These principles include precise control…
We present a comprehensive study on the directed orientational self-assembly of anisotropic nanoparticles within nematic liquid crystal droplets, driven by tunable interfacial anchoring at the substrate–liquid crystal and liquid crystal–nanoparticle…
The realization of practical lithium metal batteries depends critically on achieving stable and reversible lithium plating and stripping at the anode interface. Conventional carbonate electrolytes suffer from poor compatibility with…
This study presents the development and evaluation of a novel class of multifunctional chitosan/glycidyl methacrylate (GMA) cryogels designed for simultaneous removal of cationic and anionic dyes and effective inhibition of…
The pursuit of reliable, real-time detection systems for chemical warfare agents (CWAs) has led to widespread adoption of fluorescent sensors based on nucleophilic pyridyl moieties. These materials are designed to…
A recent study by Mantione et al. demonstrates that dimethyl fumarate (DMF) — an approved immunomodulatory drug —effectively targets chronic lymphocytic leukemia (CLL) cells by disrupting both pro-survival and inflammatory…