Name :
PSG9 Protein
Description :
Pregnancy-specific beta-1-glycoprotein 9(PSG9) is a secreted protein and contains 3 Ig-like C2-type (immunoglobulin-like) domains, 1 Ig-like V-type (immunoglobulin-like) domain. It is a member of the PSG family, a group of closely related secreted glycoproteins that are highly expressed in fetal placental syncytiotrophoblast cells. The members of the PSG protein family all have a characteristic N-terminal domain that is homologous to the immunoglobulin variable region. PSGs become detectable in serum during the first two to three weeks of pregnancy and increase as the pregnancy progresses, eventually representing the most abundant fetal protein in the maternal blood at term. PSGs function to stimulate secretion of TH2-type cytokines from monocytes, and they may also modulate the maternal immune system during pregnancy, thereby protecting the semi-allotypic fetus from rejection. PSGs are commonly expressed in trophoblast tumors. Eleven human PSG proteins (PSG1-PSG11) have been described.
Species :
Human
Uniprotkb :
Human Cells
Tag :
C-6His
Synonyms :
PS-β-G-11, PS-β-G-9, PS-β-B, Pregnancy-specific β-1 glycoprotein B, Pregnancy-specific beta-1-glycoprotein 11, Pregnancy-specific β-1-glycoprotein 9, Pregnancy-specific glycoprotein, PS-beta-B, Pregnancy-specific β-1-glycoprotein 11, PSBG-11, PS34, PSBG-9, Pregnancy-specific glycoprotein 9, Pregnancy-specific beta-1 glycoprotein B, PS-beta-G-11, Pregnancy-specific beta-1-glycoprotein 9, PS-beta-G-9
Construction :
Recombinant Human Pregnancy-specific Beta-1-glycoprotein 9 is produced by our Mammalian expression system and the target gene encoding Glu35-Ser426 is expressed with a 6His tag at the C-terminus.
Protein Purity :
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight :
65 KDa, reducing conditions
Endotoxin :
Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulatione :
Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Reconstitution :
Stability & Storage :
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
Shipping :
The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below.
Research Background :
Pregnancy-specific beta-1-glycoprotein 9(PSG9) is a secreted protein and contains 3 Ig-like C2-type (immunoglobulin-like) domains, 1 Ig-like V-type (immunoglobulin-like) domain. It is a member of the PSG family, a group of closely related secreted glycoproteins that are highly expressed in fetal placental syncytiotrophoblast cells. The members of the PSG protein family all have a characteristic N-terminal domain that is homologous to the immunoglobulin variable region. PSGs become detectable in serum during the first two to three weeks of pregnancy and increase as the pregnancy progresses, eventually representing the most abundant fetal protein in the maternal blood at term. PSGs function to stimulate secretion of TH2-type cytokines from monocytes, and they may also modulate the maternal immune system during pregnancy, thereby protecting the semi-allotypic fetus from rejection. PSGs are commonly expressed in trophoblast tumors. Eleven human PSG proteins (PSG1-PSG11) have been described.
References and Literature :
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
TIM3 Antibody Biological Activity Bupivacaine Description PMID:35151213 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com