Name :
Human GM-CSF R alpha Protein, His Tag (SPR verified)
Background :
GM-CSF R alpha(Granulocyte-macrophage colony-stimulating factor receptor subunit alpha) is also known as CSF2RA, CD116, GMR-alpha. Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells. Hereditary pulmonary alveolar proteinosis (hPAP) is a rare disorder of pulmonary surfactant accumulation and hypoxemic respiratory failure caused by mutations in CSF2RA (encoding the granulocyte/macrophage colony-stimulating factor [GM-CSF] receptor α-chain [CD116]), which results in reduced GM-CSF-dependent pulmonary surfactant clearance by alveolar macrophages.
Biological Activity :
Immobilized Biotinylated Human GM-CSF, epitope tag free, primary amine labeling (Cat. No. GMF-H8214) at 1 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.2 μg/well) plate can bind Human GM-CSF R alpha, His Tag (Cat. No. GRA-H52H7) with a linear range of 0.039-0.313 μg/mL (Routinely tested).
Species :
Source :
Human GM-CSF R alpha, His Tag (GRA-H52H7) is expressed from human 293 cells (HEK293). It contains AA Glu 23 – Gly 320 (Accession # P15509-1 ).
Tag :
Synonyms :
（Synonym）GM-CSF R alpha,GM-CSF-R-alpha,GMCSFR-alpha,GMR-alpha,CSF2RA,CSF2R,CSF2RY,CDw116,CD116
Purity :
（Purity）>95% as determined by SDS-PAGE.
Storage and Stability :
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin Level :
（Endotoxin）Less than 1.0 EU per μg by the LAL method.
Formulation :
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Protein Structure :
This protein carries a polyhistidine tag at the C-terminus.
Refactoring Approach :
Please see Certificate of Analysis for specific instructions.
Protein Labeling :
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