Name :
IL12A (Human) Recombinant Protein
Biological Activity :
Human IL12A (NP_000873.2, 57 a.a. – 253 a.a.) partial recombinant protein expressed in Escherichia coli.
Tag :
Protein Accession No. :
NP_000873.2
Protein Accession No.URL :
https://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=3592
Amino Acid Sequence :
RNLPVATPDPGMFPCLHHSQNLLRAVSNMLQKARQTLEFYPCTSEEIDHEDITKDKTSTVEACLPLELTKNESCLNSRETSFITNGSCLASRKTSFMMALCLSSIYEDLKMYQVEFKTMNAKLLMDPKRQIFLDQNMLAVIDELMQALNFNSETVPQKSSLEEPDFYKTKIKLCILLHAFRIRAVTIDRVMSYLNAS
Molecular Weight :
Storage and Stability :
Store at -20°C. For long term storage store at -80°C.Aliquot to avoid repeated freezing and thawing.
Host :
Escherichia coli
Interspecies Antigen Sequence :
Preparation Method :
Escherichia coli expression system
Purification :
Quality Control Testing :
10% SDS-PAGE Result
Storage Buffer :
In PBS (50% glycerol)
Applications :
SDS-PAGE，
Gene Name :
IL12A
Gene Alias :
CLMF, IL-12A, NFSK, NKSF1, P35
Gene Description :
interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
Gene Summary :
This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity. [provided by RefSeq
Other Designations :
IL-12, subunit p35|NF cell stimulatory factor chain 1|cytotoxic lymphocyte maturation factor 1, p35|interleukin 12, p35|interleukin 12A|interleukin-12 alpha chain|natural killer cell stimulatory factor 1, 35 kD subunit
MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
Popular product recommendations:
PD-L2 Proteinmanufacturer
FGF-18 ProteinSource
Popular categories:
Carbonic Anhydrase 5B (CA-VB)
Ubiquitin-Like Protein FUBI