Product Name :
CD28 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
CD 28 antibody CD28 antibody CD28 antigen antibody CD28 molecule antibody CD28_HUMAN antibody MGC138290 antibody T cell antigen CD28 antibody T cell specific surface glycoprotein antibody T cell specific surface glycoprotein CD28 antibody T-cell-specific surfac
Function :
CD28 (Cluster of Differentiation 28) is one of the proteins expressed on T cells that provide co-stimulatory signals required for T cell activation and survival. T cell stimulation through CD28 in addition to the T-cell receptor (TCR) can provide a potent signal for the production of various interleukins (IL-6 in particular). CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2) proteins. When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen-presenting cells (APCs). The CD86 expression on antigen-presenting cells is constitutive (expression is independent of environmental factors). CD28 is the only B7 receptor constitutively expressed on naive T cells. Association of the TCR of a naive T cell with MHC:antigen complex without CD28:B7 interaction results in a T cell that is anergic.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Synthetic peptide within human CD28 aa 170-220.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IHC-P, FC
Coupling :
unconjugated
Clone number:
RRID:
AB_3069519
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.Escitalopram oxalate Aliquot store at -20℃.Itraconazole Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.PMID:35567400 4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 25 kDa
Positive control :
Mouse spleen tissue lysate, U937 cell lysate, rat spleen tissue, human tonsils tissue, human spleen tissue, mouse spleen tissue, Jurkat.