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Articaine
CAS No. : 23964-58-1
Biological Activity：Articaine (Hoe-045 free base) is an amide anaesthetic containing an ester group, reversibly binding to the α-subunit of the voltage-gated sodium channels within the inner cavity of the nerve, can provide effective pain relief. Articaine ameliorates LPS-induced acute kidney injury via inhibition of NF-ĸB activation and the NLRP3 inflammasome pathway[2][3].
Research Area：Inflammation/Immunology
Targets：NF-κB|Sodium Channel|NOD-like Receptor (NLR)
Related Small Molecules:Akt/NF-κB/JNK-IN-1;Icariside F2;Lu AE98134;IKKγ NBD Inhibitory Peptide TFA;Mangiferin;Zandatrigine;Antioxidant agent-5;ALPK1-IN-1;Regaloside A;IMD-ferulic;SN52;Veratridine;Brompheniramine-d6 maleate;5-Aminosalicylic Acid-D3 hydrochloride;Ginsenoside Rg1;GX-674;MCC950;Echinulin;Licochalcone D;QNZ;Dibucaine;BIZ 114;NF-κΒ activator 1;Berbamine;Sodium Channel inhibitor 2;3-Deoxyaconitine
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