Yoda 1

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Yoda 1

CAS No. : 448947-81-7

Biological Activity:Yoda 1 is a potent and selective Piezo1 agonist. Yoda 1 activates purified Piezo1 channels. Yoda 1 potently inhibits macropinocytosis induced by epidermal growth factor (EGF). Yoda 1 enhances Ca2+ influx followed by activation of the calcium-activated potassium channel KCa3.1 and inhibition of Rac1 activation[2][3].

Research Area:Cardiovascular Disease

Targets:Akt|Potassium Channel|Piezo Channel|ERK

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