6-OAU

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6-OAU

CAS No. : 83797-69-7

Biological Activity:6-OAU (GTPL5846) (6-n-octylaminouracil) is an GPR84 (G protein-coupled receptor 84) agonist, with an EC50 value of 105 nM. 6-OAU works as a chemoattractant to both PMNs and macrophages, and amplifies the proinflammatory cytokine IL-8, shows proinflammatory function. 6-OAU also displays anti-bacterial function[2].

Research Area:Inflammation/Immunology

Targets:Bacterial|Antibiotic|GPR84|ERK

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