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Dehydrocorydaline chloride
CAS No. : 10605-03-5
Biological Activity：Dehydrocorydaline chloride (13-Methylpalmatine chloride) is an alkaloid that regulates protein expression of Bax, Bcl-2; activates caspase-7, caspase-8, and inactivates PARP. Dehydrocorydaline chloride elevates p38 MAPK activation. Anti-inflammatory and anti-cancer activities[2]. Dehydrocorydaline chloride shows strong anti-malarial effects (IC50 =38 nM), and low cytotoxicity (cell viability > 90%) using P. falciparum 3D7 strain[3].
Research Area：Cancer|Infection
Targets：Parasite|PARP|Autophagy|p38 MAPK|Bcl-2 Family|Caspase
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