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Idoxuridine
CAS No. : 54-42-2
Biological Activity:Idoxuridine (5-Iodo-2′-deoxyuridine, 5-IUdR, IdUrd) is an iodinated thymidine analogue that competitively inhibits phosphorylases. Idoxuridine can inhibit viral activity, particularly viral eye infections, including herpes simplex keratitis, by inhibiting DNA polymerase and affecting viral replication. Idoxuridine against feline herpesvirus has the IC50 value of 4.3 μM. Idoxuridine shows anti-orthopoxvirus activity.
Research Area:Infection|Cancer
Targets:Orthopoxvirus|Phosphatase
Related Screening Libraries:Covalent Screening Library Plus;Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Anti-Infection Compound Library;Metabolism/Protease Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Antiviral Compound Library;Drug Repurposing Compound Library;Covalent Screening Library;Nucleotide Compound Library;Anti-COVID-19 Compound Library;NMPA-Approved Drug Library;FDA Approved & Pharmacopeial Drug Library;Drug-Induced Liver Injury (DILI) Compound Library;Phosphatase Inhibitor Library;Rare Diseases Drug Library;FDA-Approved Anticancer Drug Library;Human Metabolite Library;Anti-Orthopoxvirus Compound Library;
Related Small Molecules:GNF362;ZLDI-8;Uralenol;Thymidine-13C5,15N;SHP504;Trimyristin;Coumermycin A1;SHP099 hydrochloride;MY10;Vidarabine;PTP1B-IN-3 diammonium;Fialuridine;Calyculin A;LMPTP inhibitor 1 dihydrochloride;[pTyr5] EGFR (988-993) (TFA);RMC-3943;AS1949490;PGAM1-IN-1;TD52 dihydrochloride;bpV(phen);EDP-305;CCT007093;(E/Z)-Icerguastat;ARL67156 trisodium;Netropsin dihydrochloride
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