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Methylene Blue

CAS No. : 61-73-4

Biological Activity:Methylene blue (Basic Blue 9) is a guanylyl cyclase (sGC), monoamine oxidase A (MAO-A) and NO synthase (NOS) inhibitor. Methylene blue is a vasopressor and is often used as a dye in several medical procedures. Methylene blue through the nitric oxide syntase/guanylate cyclase signalling pathway to reduce prepulse inhibition. Methylene blue is a REDOX cycling compound and able to cross the blood-brain barrier. Methylene blue is a Tau aggregation inhibitor. Methylene blue reduces cerebral edema, attenuated microglial activation and reduced neuroinflammation[2][3].

Research Area:Cancer|Infection|Neurological Disease

Targets:Microtubule/Tubulin|Monoamine Oxidase|Guanylate Cyclase|NO Synthase

Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;Bioactive Compound Library Plus;

Related Small Molecules:Carboxy-PTIO potassium;Cinaciguat hydrochloride;Tirbanibulin dihydrochloride;Valeriandoid F;PXS-4728A;Ciwujianoside C3;Tilavonemab;NOS-IN-3;Regaloside A;Tau tracer 1;Hypericin;Dolastatin 10;Aminopicoline;Simtuzumab;SSAO inhibitor-1;trans-Isoferulic acid;Ceratamine A;Batabulin sodium;DETA NONOate;OXi8007;Antitumor agent-68;Chondroitin sulfate;Dictyostatin;Tubulin inhibitor 6;Oryzalin;Tubulin inhibitor 25

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