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Hemicholinium 3
CAS No. : 312-45-8
Biological Activity：Hemicholinium 3 is a competitive inhibitor of the high affinity choline transporter (HACU) with a Ki value of 25 nM. Hemicholinium 3, a neuromuscular blocking agent which inhibits the synthesis and the release of acetylcholine (ACh). Hemicholinium 3 inhibits the Epibatidine-evoked contraction and [3H]acetylcholine release with IC50s of 897 nM and 693 nM, respectively[2].
Research Area：Neurological Disease
Targets：Cholinesterase (ChE)
Related Screening Libraries:Bioactive Compound Library Plus;Neuronal Signaling Compound Library;
Related Small Molecules:Piperilate;BuChE-IN-5;AChE/BChE-IN-10;Timosaponin AIII;Trimyristin;AChE-IN-10;Isoimperatorin;Pseudocoptisine chloride;Itopride-d6 hydrochloride;Sinapine thiocyanate;sEH/AChE-IN-1;AChE-IN-11;Heliosupine;(-)-Cyclopenin;Leptomerine;eeAChE-IN-1;HDAC6-IN-6;Corydaline;Cyclanoline chloride;AChE-IN-20
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