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Fangchinoline
CAS No. : 436-77-1
Biological Activity：Fangchinoline is isolated from Stephania tetrandra with extensive biological activities, such as enhancing immunity, anti-inflammatory sterilization and anti-atherosclerosis. Fangchinoline, a novel HIV-1 inhibitor, inhibits HIV-1 replication by impairing gp160 proteolytic processing. Fangchinoline targets Focal adhesion kinase (FAK) and suppresses FAK-mediated signaling pathway in tumor cells which highly expressed FAK[2]. Fangchinoline induces apoptosis and adaptive autophagy in bladder cancer[3].
Research Area：Cancer|Infection
Targets：Autophagy|HIV|FAK|Apoptosis
Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Anti-Infection Compound Library;Apoptosis Compound Library;Kinase Inhibitor Library;Protein Tyrosine Kinase Compound Library;Natural Product Library;Anti-Cancer Compound Library;Antiviral Compound Library;Autophagy Compound Library;Macrocyclic Compound Library;Phenols Library;Cytoskeleton Compound Library;Traditional Chinese Medicine Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Alkaloids Library;Anti-Pancreatic Cancer Compound Library;Anti-Cancer Natural Product Library;Antiviral Traditional Chinese Medicine Active Compound Library;Plant-Sourced Natural Product Library;Anti-Pulmonary Fibrosis Compound Library;
Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;BJE6-106;Dinaciclib;HIV-1 TAT (48-60);Ecteinascidin 770;MDM2-p53-IN-15;Seletracetam lithium;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;HIV-IN-2;Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5;Apoptosis inducer 9
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