For research use only. We do not sell to patients.

EGFR/BRAF-IN-1

Biological Activity：EGFR/BRAF-IN-1 (compound 21), a 2,3-dihydropyrazino[1,2-a]indole-1,4-dione derivative, is a potent EGFR/BRAF inhibitor with an IC₅₀ of 45 nM for BRAF^V600E. EGFR/BRAF-IN-1 inhibits cancer cell proliferation (GI₅₀=35 nM). EGFR/BRAF-IN-1 shows good antioxidant activity.

Research Area：Cancer

Targets：EGFR|Raf

Related Small Molecules:Avutometinib;NSC81111;pp60 (v-SRC) Autophosphorylation Site, Phosphorylated;BMS-690514;AZ 628;Osimertinib-13C,d3;EGFR-IN-5;FGFR2-IN-3;Genistein;Epertinib hydrochloride;UNC-CA359;Osimertinib mesylate;AV-412 free base;Nelipepimut-S;Falnidamol;HER2-IN-6;PROTAC EGFR degrader 7;CHMFL-EGFR-202;Everafenib;Avitinib;Naquotinib

Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Fluorescent Dye  |  PROTAC  |  Isotope-Labeled Compounds  |  Oligonucleotides

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• Structurally and synthetically diverse biologically active compounds；
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Structurally and synthetically diverse biologically active compounds；

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