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Calcimycin
CAS No. : 52665-69-7
Biological Activity：Calcimycin (A-23187) is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). Calcimycin induces Ca2+-dependent cell death by increasing intracellular calcium concentration. Calcimycin inhibits the growth of Gram-positive bacteria and some fungi. Calcimycin also inhibits the activity of ATPase and uncouples oxidative phosphorylation (OXPHOS) of mammalian cells. Calcimycin induces apoptosis[2][3][4].
Research Area：Cancer|Infection
Targets：Fungal|Autophagy|Bacterial|Antibiotic|Apoptosis
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