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Bimiralisib

CAS No. : 1225037-39-7

Biological Activity：Bimiralisib (PQR309) is a potent, brain-penetrant, orally bioavailable, pan-class I PI3K/mTOR inhibitor with IC₅₀s of 33 nM, 451 nM, 661 nM, 708 nM and 89 nM for PI3Kα, PI3Kδ, PI3Kβ, PI3Kγ and mTOR, respectively. Bimiralisib is an mTORC1 and mTORC2 inhibitor.

Research Area：Cancer

Targets：mTOR|PI3K

Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Kinase Inhibitor Library;PI3K/Akt/mTOR Compound Library;Stem Cell Signaling Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;CNS-Penetrant Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Antioxidant Compound Library;Differentiation Inducing Compound Library;Reprogramming Compound Library;Oxygen Sensing Compound Library;Anti-COVID-19 Compound Library;Glycolysis Compound Library;Cytoskeleton Compound Library;Orally Active Compound Library;Glutamine Metabolism Compound Library;Anti-Breast Cancer Compound Library;Anti-Lung Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Obesity Compound Library;Angiogenesis-Related Compound Library;Lipid Metabolism Compound Library ;Glucose Metabolism Compound Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;Anti-Prostate Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;Cancer Stem Cells Compound Library;

Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Umbralisib hydrochloride;Topoisomerase I/II inhibitor 3;Cyclovirobuxine D;Rigosertib sodium;Tenalisib R Enantiomer;PI3kδ inhibitor 1;WYE-354;PI3K/VEGFR2-IN-1;L-Leucine-1-13C,15N;1,3-Dicaffeoylquinic acid;PI3Kδ-IN-1;PI-103-d8;Palomid 529;PI3Kα-IN-8;PI-103 Hydrochloride;RMC-5552;OXA-01;L-Leucine-15N;IC-87114;PI3K/mTOR Inhibitor-6;PI3K-IN-10;SF2523;PI3K-IN-29;PI3K/mTOR Inhibitor-1;PI3K-IN-26;GSK-F1;Serabelisib

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