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ABT-724
CAS No. : 70006-24-5
Biological Activity:ABT-724 is a potent and highly selective dopamine D4 receptor agonist with an EC50 of 12.4 nM for human dopamine D4 receptor. ABT-724 is a potent partial agonist at the rat D4 (EC50 of 14.3 nM) and the ferret D4 receptor (EC50 of 23.2 nM). ABT-724 has no effect on dopamine D1, D2, D3, or D5 receptors. ABT-724 could be useful for the treatment of erectile dysfunction and has favorable side-effect profile.
Research Area:Neurological Disease
Targets:Dopamine Receptor
Related Small Molecules:Alizapride hydrochloride;Thioproperazine;Bromopride-d3;Nuciferine;Glaucine;SB-277011 dihydrochloride;MIF-1 TFA;Sulpiride;(Rac)-Razpipadon;Clebopride malate;WAY-100635;Flupentixol-d4 dihydrochloride;Cariprazine-d6 hydrochloride;Itopride-d6 hydrochloride;ONC206;Brexpiprazole S-oxide;cis-(Z)-Flupentixol dihydrochloride;D4R antagonist-1;U91356
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