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α-Lipoic Acid

CAS No. : 1077-28-7

Biological Activity：α-Lipoic Acid (Thioctic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid inhibits NF-κB-dependent HIV-1 LTR activation^[2][3]. α-Lipoic Acid induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells^[4]. α-Lipoic Acid can be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, which has improved antitumor efficacy than CPUL1^[5].

Research Area：Cancer|Infection|Inflammation/Immunology

Targets：NF-κB|HIV|Endogenous Metabolite|Apoptosis|Mitochondrial Metabolism

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